Qian Wang Dept. of Chemistry, University of South Carolina
Event Date:
February 11, 2013 – 4:00 PM to February 12, 2013 – 3:59 PM
Location:
Burson 115
Event Date:
February 11, 2013 – 4:00 PM to February 12, 2013 – 3:59 PM
Location:
Burson 115
SEMINAR SERIES
SPRING 2013
Qian Wang
University of South Carolina
Will be presenting
“Learning from Virus – A Facile Route to Generate Core-Shell
Nanoparticles with Functional Protein Corona”
Abstract:
The investigation of protein-polymer or protein-nanoparticle interaction is critical for the development of novel biomaterials and hierarchically assembled nano-architectures. Among them, the polymer-protein core-shell nanoparticles (PPCS-NPs) are the most common structures which offer many advantages in the field of medicine and energy applications. Here we show that PPCS-NPs can be prepared based on synergistic interactions between proteins and synthetic polymers, a strategy learning from virus assembly. This facile and versatile process can yield structural well-controlled core-shell structures, in which proteins stay as the corona and still maintain their original biological activities. A few cases studies will be presented to highlight the application potential of such core-shell nanostructures in drug delivery, antigen presentation and enzymatic reactions.
Monday, February 11, 2013 @ 4:00pm Rm. 115 Burson
Refreshments served @ 3:45